![]() In the Run box type outlook.exe /resetnavpane, then press the Enter key or click on the OK button.Press the Windows + R key to open the Run dialog box.Before moving to the next steps, make sure Outlook is completely closed on your computer.To execute this command to resolve the issue and to do this, you can follow the given steps: If Outlook won’t open on Windows 10 computer, then you may run the resetnavpane command to fix this issue. If everything seems working fine to you, then get back to your original profile and verify whether the “Microsoft Outlook will not open” problem resolved or not. Open Outlook and choose the new profile from the dropdown list and click on the OK button.Now, select the “Prompt for a profile to be used” option and then choose OK.Click on the Finish button, and now you will see a new profile is added to the General tab of Mail window.Enter all the details and click on the Next button.In the Mail window, click on the Add button.Now, click on the Show Profiles button.Press the Windows + X key to open the Quick Access Menu.For this, you can follow the given steps: To resolve this issue, you are required to create a new account. If your Outlook profile is corrupted, then you might undergo the Microsoft Outlook won’t open in Windows 10 issue. After finding the problematic add-in, disable it.Repeat this step until you find the add-in causing this issue. Now enable the next add-in and again close and restart the Outlook.Click on the Add-ins and then enable one add-in.Again go to the File and click on the Options.In the Run box, type Outlook, then press the Enter key or click on the OK button.To do so, follow the below-given instructions: Now, enable the add-ins one-by-one to check which add-in is causing the “Outlook not opening” issue on your Windows 10 computer. ![]() Click on the OK button and close the Outlook.Īfter disabling all the add-ins, reopen the Outlook.Clear all the checkboxes to disable the Add-ins.In the COM Add-ins window, remember all the add-ins enabled under the Add-ins available section.Under the View and manage Office Add-ins section, make sure “ COM Add-ins” is selected in the Manage box.Now in the Outlook Options window, click on the Add-ins. ![]()
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